The large variability of soil parameter causes that the overall stability of dock slope often has large uncertainty.The reliability analysis of a dock slope is carried out considering the variability of the soil cohesive force and internal friction angle in order to analyze the overall stability of the dock slope more accurately and reduce the uncertainty in the stability analysis.The slope stability numerical simulation software Slide is used to obtain the deterministic safety factor on the basis of the rigid body limit equilibrium analysis.Then according to the measured soil parameter distribution of the dock slope,the response surface method and the first-order second moment method are used to calculate the reliability of the dock slope.The results show that the safety factor based on the deterministic analysis of the standard value of soil parameters is one-sided to the reliability evaluation of the dock slope,and the stability of slope based on the reliability analysis is closer to the actual situation.In the actual engineering design and construction,the safety factor and reliability of the slope should be considered comprehensively.