The non-stop construction at important sharp channel bends leads to many passing ships，frequent water level changes，and poor visibility. Therefore，ensuring traffic safety during construction has been a technical problem for the construction unit. For the waterway regulation project of Laokou Junction on the Guangxi Yujiang River，this study considers the natural geographical characteristics such as severe backflow in the downstream deep pool of the construction section and the traffic and transportation conditions during the construction period. It adopts the method of combining blasting in the strips and layers，with the medium- and deep-hole benches as the main and shallow holes as the auxiliary. Upstream dredging shall be before downstream dredging，and the design of the overburden layer and excavation slope shall take into account the excavation slope value designed for offshore reef cleaning. The excavation scope of the water area within the design bottom line of the channel shall meet the design requirements，and the excavation section shall not be less than the design excavation section. In addition，shallow spots are strictly prohibited in the water area within the design bottom line. The construction combination of land blasting and water slag removal can avoid comprehensive construction and the occupancy of the channel width and reduce the impact on passing ships.