For driven piles in the soft rock stratum，there is currently no accepted method to evaluate the side resistance. For the rock socketed steel pipe pile foundation of Panama Amador cruise terminal，nine groups of dynamic tests of pile foundation have been carried out，and the side resistance of pile has been obtained by wave equation analysis method. The distribution law of pile side resistance in stratum and the relationship between pile side resistance and uniaxial compressive strength in rock stratum has been studied. The conclusions are as follows：1）The distribution curve of side resistance is in parabola form，and four strata can be distinguished obviously，which are soft clay，silty sand，strongly weathered rock，and moderately weathered rock. The part after the curve falls is defined as the rock socketed section. Based on this，the rock-socking depth of pile A-4 is 6 m，and the rock-socking depth of other piles is 4m，which meets the design minimum rock-socking depth of 3m. 2）The pile side resistance compressive strength （UCS） curve of rock stratum is exponential distribution，and non-linear distribution. 3）In the soft rock stratum，the side resistance plays a leading role. With the same UCS value，the pile side resistance in argillaceous siltstone is obviously larger than basalt. 4） With the increase of UCS，the self-stability of rock mass gradually enhances，and the friction coefficient gradually changes into the dominant factor affecting the side resistance. After UCS increases to a certain value，the pile side resistance tends to be stable. 5） The relationship between pile side resistance and compressive strength in the rock stratum is obtained，which can provide a basis for estimating pile side resistance in the rock stratum.