Based on the elastic-plastic finite element model of the sandy slope and shaking table test，we study the influence laws of dynamic pore water pressure on the dynamic response.The results show that the dynamic pore water pressure of the slope toe increases obviously，and it is the destroyed position under the influence of dynamic pore water pressure，thus it should be taken as the key protection in the actual engineering location.The dynamic pore water pressure decreases with the increase of the average effective stress；The existence of dynamic pore pressure causes the destruction of the slope quickly.The pore pressure caused by the average principal stress increment has nothing to do with the nonlinear deformation characteristics of soil.Without considering the groundwater，the destruction of slope appears on the top of the slope and it shows the obvious lash effect，while the destruction appears on the slope toe.The dynamic pore water pressure values under the action of indoor test are greater than that under the numerical simulation values.However，the maximum deviation is controlled within 15% which verifies the accuracy of the numerical simulation results.