Seismic isolation design has developed rapidly in recent year,and has been widely used in the field of civil buildings,roads and bridges with good effect,but the seismic isolation design has no obvious effect on conventional docks.For pile supported LNG pier,due to their high requirements for seismic design,the seismic load usually serve as the control function of the structure,especially in high seismic regions,so it is more suitable to adopt seismic isolation design.Referring to the practice of other industries,this paper recommends the isolation design method suitable for pile supported LNG pier.In structural design,a scheme combining with prefabricated structure is proposed,which has the advantages of rapid construction and timely replacement.The research results can provide reference for the design of pile supported LNG pier in strong earthquake area.