In view of the decrease of water level caused by the decrease of minimum navigable flow at the Danjiangkou to Huangjiagang section after the implementation of the Yangtze River Diversion Project and Hanjiang River Reinforcement Project,the comprehensive regulation project of Danjiangkou to Huangjiagang section of Hanjiang River is studied.A two-dimensional flow mathematical model is used to simulate and compare the navigation flow conditions of the waterway before and after the implementation of the comprehensive regulation project.The results show that the implementation of comprehensive regulation project can effectively improve the navigation water flow conditions,solve the problem of reducing navigation standards in local river sections due to the reduction of minimum navigation flow and water level,and provide technical support for the implementation of the South-to-North Water Diversion Project.