Regarding the loads on the track beam of a gantry crane under eccentric loading，this paper investigates the loads on a track beam and foundation settlement and obtains the loads on the track beam and the settlement displacement of the foundation under eccentric loading by the elastic foundation beam method and a numerical analysis method. The conclusion is that the required areas for upper longitudinal reinforcement，lower longitudinal reinforcement，and stirrup when the track beam is under eccentric loading increase by 17.08%，56.83%，and 16.5%，respectively，compared with those in the case of axial loading. The ultimate design wheel load under the ultimate load-carrying capacity of the structure is 1 197.2 kN/m，which is 2.55 times the design wheel load of 250 kN/m. However，the deformation of the foundation under the design wheel load reaches 39.67 mm and is close to the value required by the specification，indicating that deformation control is a major factor in foundation design.