The exit of the Babao ship lock connecting the Grand Canal and Qiantang River is located in the strong tidal bore reach of the Qibao bend，where the water flow and sediment conditions are extremely complex. Comprehensive regulation measures should be taken to meet the navigation requirements. In view of the river regime change，channel depth，flow conditions for navigation，sediment deposition in the downstream approach channel of the ship lock，and the navigation assurance rate at the exit of the lock，comprehensive methods and means are applied for an in-depth study，including the riverbed evolution analysis，mathematical model calculation of tidal flow and sediment，physical model test，and ship model and vessel maneuvering test. The comprehensive regulation scheme for the beach at the exit of the lock is verified. The results show that by clearing the residual dam，shortening the length of spur dikes，adding navigation dikes，and other engineering measures，we can make the main channel close to the exit of the ship lock，significantly improve the navigation assurance rate of the entrance area，and ensure that the sediment deposition in the downstream approach channel of the ship lock and the entrance area is within the controllable range.