This paper aims to study the structural selection of a wharf under complex geological conditions in the open sea. Taking a 300，000-ton unloading wharf project in Ningbo as an example，the paper selects an inclined rock-socketed pile and a vertical rock-socketed pile as research objects according to the structural arrangement adaptability，construction technology，and construction cost with the consideration of hydrogeological characteristics. A comparative analysis method is used to analyze the above two pile arrangements technologically and economically. The results show that compared with the vertical rock-socketed pile with a large diameter，the inclined rock-socketed pile has the advantages of small pile diameter，strong tolerance to horizontal load，and low engineering cost，thus being more suitable and economical. In terms of the construction technology of the inclined rock-socketed pile，rotary drilling rigs have high reliability in construction quality. Regarding pile stabilization measures during the construction period，it is practical to use the gravel foundation bed to ensure the stability of the rock-socketed pile，which is suitable for the relatively short construction period in the open sea.