To promote the development of high-strength and high-performance concrete technology of marine mechanized sand in marine concrete structures，we study systematically the influence of granite powder on the workability，mechanical property，chlorion penetration resistance of C80-HSHPC，and analyze the influential mechanism of stone powder on concrete performance. The results show that the workability of C80 HSHPC is good when the content of machine-made sand powder is between 4.5% and 6.5%，and the effect of stone powder content on the yield stress，plastic viscosity and other rheological properties of freshly mixed concrete is not obvious. With the increase of stone powder content，the mechanical properties of HSHPC increase first and then decrease. The chloride ion permeability and drying shrinkage increase continuously. However，the effect is not obvious when the content of stone powder is less than 6.5%. Appropriate amount of stone powder reduces the porosity of concrete and optimizes the distribution of pore structure. It is beneficial to improve the mechanical properties and durability of concrete. However，when the content of stone powder exceeds 6.5%，stone powder has negative effect on the hydration process and pore structure. The content powder of manufactured sand should be controlled at 4.5%~6.5%.