To analyze the differences of various national codes in reliability design regulations，we select European，British and American codes，and carry out a comparative analysis of the main contents of structural reliability design regulations，i.e. safety grade，design working life，the minimum target reliability index，design situations，as well as the limit state design expressions. Combining overseas engineering practice，we conduct structural internal force calculation and choose typical concrete structural members to design according to various codes. The results show that although all codes recommend the limit state design method based on reliability，there are differences in action calculation，partial factors，combination factors and design expression，resulting in different design results based on codes of different countries.