With the implementation of large-scale reclamation projects and bank-protection works in recent years，the boundary of North Branch of the Yangtze Estuary gradually maintains stable. In general，the North Branch slowly undergoes sedimentation，but the remarkable channel evolution still occurs in some local regions with its complex navigation conditions. Based on the topographic data，we analyze the characteristics of channel evolution and navigation-obstruction of the North Branch since 1997，and propose the regulation idea of “linkage regulation and hierarchical navigation” in the upper，middle，and lower reaches of the North Branch channel. The water-depth of the upper reach of Chongqi Bridge mostly ranges from 3 m to 5 m，with the groove deeper than 3 m only being interrupted near Chongtou. It is suggested to arrange the channel with natural depth in the upper reach，and dredge in some shallow areas. The lower reach of Chongqi Bridge is widened，with the water-width from 5 km to 10 km. Also，the floodplain flow increases because of the erosion and shrink of the central bar，and it is not conducive to the maintenance of channel depth. It is suggested that the regulation works should be taken on the south bank，and the protection project of the central bar is carried out to stabilize the channel boundary and maintain the channel depth.