To choose the best channel regulation scheme of the Liantuo section of the Yangtze River，this paper analyzes the influential factors of channel regulation and constructs the regulation scheme evaluation index system：18 indexes from the aspects of construction condition，ecological impact，remediation effect，and economic effect are taken into consideration in this evaluation index system. Adopting the fuzzy comprehensive evaluation model based on the evaluation index system to evaluate and optimize the waterway regulation project scheme of the Liantuo section of the Yangtze River，this paper concludes that the scheme 1（reef explosion+slag removal+ deep-pool filling） has a high degree of affiliation and achieves a higher number of excellent indicators. Thus the scheme 1 is recommended as the better channel regulation scheme.