The single-well tower structure greatly improves the synchronicity of water level vertical shaft of the hydro-floating ship lift，but with the increase of the lifting height，the greater the water depth in the vertical shaft is，and the more prominent the problems of lateral wall displacement and the excessive bending moment become. Taking the 150-meter-class single well tower column as an example，this paper puts forward the assumption of opposite-tensile cable arrangement in the shaft and simplified cable arrangement scheme. Based on the optimization method of the weight allocation coefficient of cable tension，the optimal solution of the density distribution of cable equal stress is obtained，and the solution is discretized into the equivalent equal load arrangement scheme，which can be applied in practical engineering. The results of the finite element model show that the maximum displacement can be reduced by 47.44% in the equal-load layout compared with the simplified scheme，and there is little difference between the extreme values of the longitudinal and longitudinal bending moments. Compared with the cable-free scheme，the maximum displacement，longitudinal moment and vertical moment can be reduced by 93.5%，74.36%，and 75.84%，respectively. The prestressing scheme of high strength steel cable deserves further study.