Based on channel regulation of creek mouth-bar rapids in the Lancang River Ⅳ level channel construction engineering, aiming at the problems that it needs to improve the level of the channel and it is necessary to guarantee the stability of navigation channel during the channel regulation process of creek mouth-bar rapids, this paper analyzes the cause of creek mouth-bar rapids from the water flow and sediment motion features, historical regulation and the incoming water and stone features, proposes building retaining dam for falling stone, building diversion and perennial dredging to improve the channel scale and maintain the channel stability.The results show that the engineering measures of retaining, guiding and dredging are used in the process of waterway regulation of creek mouth-bar rapids, which can solve the problems of creek mouth-bar rapids and provide references for the similar projects.