pre-stressing simple support box beam has stable structure,good section rigidity,excellent tensional strength,light weight and small material usage,but the application is fairly less in wharf engineering than railway and highway engineering.For the design problems of pre-stressing simple support box beam in wharf engineering,this paper combines the project example to analyze the selection of structural types,operational requirement,calculation of internal forces,sectional reinforcement and stress checking calculation.The results show that wharf track beam is used by post-tensioned pre-stressing single box double room simple support box beam,and it can satisfy the requirements of long span and high load,thus it can optimize the scheme selection,plane layout and structure selection of large deepwater berth.