Strict traffic control of LNG ships when entering and leaving the terminals has an impact on port operation.As a result,it is necessary to make a careful decision on the location and layout of the LNG terminals in the stage of planning.A systematic study is conducted based on a self-developed software of The simulation system of terminal operation based on multi-agent information interaction V1.0,the complicated port transport system with the effect of a LNG terminal is built.A real case is introduced to this study,and the research flow and method of effect by the navigation of LNG vessels in short and long terms are discussed.Combining with the characteristics of navigation environment,the optimization measures are put forward.The results could be employed to port planning.