In order to improve the simulation precision of storm surge,we superimpose typhoon wind field and NCDC background winds together and also consider the influence of astronomical tides on storm surge.By using the two dimensional hydrodynamic model MIKE21,the storm surge in Jiangsu sea area is simulated during No.1210 typhoon Damrey period.The influences on simulation results by applying different formulas of pressure flied and radius of maximum wind speed are discussed,and the best combination to analysis the flow flied is selected.The simulation results show that the storm surge caused by typhoon can be simulated well by this model,and the results of the combination of Holland’s pressure flied formula and Jiang Zhi-hui’s radius of maximum wind speed agree better with the measured value.