This paper presents a optimization scheduling method on cascade navigation hubs based on waterway hydrodynamic calculation.By dividing the whole channel into some sections and setting virtual sections at the junctions positions,the water level and flow process hydraulic factors of the virtual channel crosses and the natural crosses will be determined by solving Saint Venant equations and water balance calculation considering hub scheduling.Thus,hydraulic factors of all sections of full channel can be computed synchronously and meet the high accuracy requirements of the flow channel level and entrance during the navigation hubs cascade dispatching periods.Joint optimization scheduling model of the navigation hub cascade is built,which can canalize the waterway and improve the entrance area and the navigation flow conditions and optimize the generation strategy,and thus realize the cascade of navigation and power generation comprehensive utilization benefit maximization.Example of Qujiang traffic hub cascade results show that the constructed model is more accuracy and improve the cascade navigable guarantee rate and total generating capacity.