Taking Changde Damen crane wharf (a variable stiffness frame wharf) project for example,we establish several frame wharf three-dimensional finite element models.After analyzing and researching the deformation characteristics of variable stiffness frame wharves under different working conditions that ship percussive horizontal force is impacted at different water levels,we compare different overall deformations of frame wharves with or without vertical diagonal bracing and horizontal diagonal racing,and optimize the frame wharf structure by setting vertical diagonal bracings without setting horizontal diagonal racings.The optimized structure not only decrease the overall deformation of the frame wharf under the complex load condition,but also strengthen the frame wharf structural integrity and structural reliability with a reasonable cost.