Valve cavitation problem is the most critical technical problem in the design of high-head lock.Serious cavitation of the lintel and the hemline will arise the “vibroacoustic” phenomenon,which will lead to denudation of valve panel and corridor concrete,and thus seriously affect the engineering quality and safety.The cavitation defense measures for the lock valve are researched based on the actual engineering and satisfactory results are obtained.The research methods and measures are applicable to most cases,so they may serve as reference for the similar engineering.