To provide a technical support for the regulation work of Liyushan waterway in the mid-reach of the Yangtze River,we research the regulation principles and implementation schemes.Based on the analysis of the recent navigational conditions of Liyushan waterway and its negative evolution tendency,we propose the regulation principles,i.e.,taking the north channel as the main navigation channel,to stabilize the current river regime and channel-shoal layout by protective engineering,control the development of the south channel and improve the navigation condition of the north channel.With the help of physical model tests,we recommend the general regulation scheme for the waterway regulation,which ensures to satisfy the planned channel dimensions of year 2020.