In order to study the numerical simulation techniques and vertical capacity characteristics of large- diameter PHC pipe pile, based on high-piled wharf of Zhuhai Gaolan port, we conduct the numerical simulation on large-diameter PHC pipe piles of the wharf by ABAQUS, the result of which is validated by comparing with that by the field test. Then we study the vertical compression Q-S curves of PHC pile through changing the parameters of pile diameter, pile length, soil of pile shaft and pile toe etc. The results show that the displacement value of numerical simulation is about 2% to 20% smaller than that of the field test in the loading process, and the length of pile which is larger than 50 m belongs to super long pile.