Based on the off-shore wharf engineering of the Zhongke Refinery & Petrochemical Company, the uplift wave-pressure and wave-force on pier on piles are researched by wave physical model tests. Firstly, the process and distribution of wave pressure on the undersurface of pier are analyzed under different conditions of relative ultrahigh (height between pier and water surface), the two different types of pressure (pressure of impact and pressure of wave) are discussed, and the relationship between the relative synchronous pressure on the undersurface of pier and relative ultrahigh is proposed. Secondly, the process of uplift wave force on pier is analyzed under different conditions of relative ultrahigh, and is compared with relative pressure. At last, the result of different computing methods of relative uplift wave force on pier is compared with the result of physical model test. The research provides reference about uplift wave force on pier for other off-shore wharf engineering.