The inlet river of the south channel and north channel is one of those with the most frequent change in the Yangtze estuary. Based on the analysis of river bed evolution and control effect of the south and north channel inlet project, this paper probes into the riverbed evolution trendy and further regulation strategy under new situation. The result shows that under the new situation, the inlet river of the south channel and north channel is still characterized with unstable factors, featuring especially the uncontrolled Biandan bar and the increasing impact-resistant brush pressure of regulation buildings. The regulation scheme proposed countering the unstable factors is proved effective and feasible by the tidal current mathematical model research.