With the rapid development of port information-based construction, and mature using of wireless sensor, wireless network, and video surveillance, it is feasible to construct dangerous goods monitoring and warning system combining port logistics hub dangerous goods operating features. On the basis of analyzing the function requirement of dangerous goods monitoring and warning system of port logistics hub, this paper proposes the five-storey system frame, i.e. information collection layer, information transmission layer, information management layer, support platform layer and information application layer. Meanwhile, this paper analyzes the key technology of information collection and processing, and prospects the follow-up research direction.