During the operation of the inshore channel, the channel sedimentation will happen due to moving of sand material under the effect of tide, wave and current. Thereby, the periodic maintenance upon the channel is required. However, the maintenance cost will be reduced once a reasonable channel layout and slope design is adopted. Based on the natural conditions and water level data of Ras Az Zawr port, Saudi Arabia, we analyze the trend of sedimentation of channel and the reason for it by theoretical analysis and numerical simulation. On that basis, we propose suggestions for the logical channel slope , which will cut down the maintenance cost of navigation channel. Based on the analysis of the mathematic parameter and verification of survey data during a period of operation, we know that the channel layout and slope design of Ras Az Zawr port is reasonable and acceptable.