This paper analyzes the main factors of the general layout of Rizhao-Yizheng 300 000 DWTcrude oil wharf, including the relationship between the crude oil wharf project and the overall planning, naturalconditions of the engineering region, as well as the relationship with the neighboring projects, etc., and researchesthe key technology including wharf axial line and wharf layout. The research results may serve as reference forthe design large oil wharves.