The paper uses historical research results of Yangtze estuary and recent flow, sediment and topographic data to analysis and summary of flow and sediment character and regulars of riverbed evolution change, and predict riverbed evolution trend of Yangtze estuary. The results show that since the construction of Yangtze estuary deep-water channel regulation engineering, the river regime remained stable overall, construction of this engineering and the south-north channels engineering are important to remained river steady. The basic law of flow and sediment transport in Yangtze estuary has no obvious change. The upstream inflow and sediment changes cause some changes of foreshore and deep channels, but it’s not obvious of north deep-water channel, the river regime is still basically according to the recent trend of development, it should pay highly attention to some adverse trends of river, it should take some corresponding engineering measures when it’s necessary.