With the development of harbor construction，prestressed concrete pipe piles are more and more widely used in harbor civil engineering. This paper probes into the structure of prestressed concrete pipe piles,piling technology and quality inspection after construction based on the design and construction experience of port land area building engineering, according to the geologic condition of the construction site, and through analyzing the characteristics of the prestressed concrete pipe piles and the piling mechanism, also referencing related documents and information. Some suggestions on the improvement are put forward to serve as a reference for the design and construction.