There are many important liquefied natural gas (LNG) ports planned in the waters of Zhoushan Islands，which play a key role in ensuring the natural gas supply in the Yangtze River Delta.The LNG terminals have the characteristics of high self-construction requirements and strong external exclusivity，and it is technically difficult to construct such terminals in the open island and reef waters represented by the Zhoushan Islands.Taking Zhoushan Liuheng and Yangshan LNG terminals as examples，this paper systematically analyzes the influence of open island and reef waters on the planning and layout of LNG terminals，discusses key issues in terminal and channel layout，and demonstrates the safety spacing of joint layout of multiple large LNG berths.Considering the influence of ship navigation safety and navigation efficiency in LNG terminals，this paper proposes the LNG terminal planning and layout scheme.The results show that when multiple large LNG berths are arranged in an open water environment，the safety spacing should be appropriately increased compared with when the cover conditions are better，and attention should be paid to the influence of crosswind and inclined top flow to ensure the safety of ship navigation.It is also necessary to control the reasonable scale of LNG transportation，adopt optimal navigation measures，and improve ship navigation efficiency.