Coral sand is a special kind of geotechnical material widely distributed in countries participating in the Belt and Road Initiative. Due to its engineering characteristics of breakability，large deformation and high compressibility，the applicable technology and final reinforcement effect of the foundation treatment are different from those for the ordinary terrestrial sand to some extent. In an actual project，we carry out vibro-compaction tests to investigate the various technological parameters of filling the coral sand foundation. The results show that for the surface of coral sand，reverse insertion and vibration time increase can effectively improve the soil compactness between piles. Regarding the bottom medium-density coral sand layer，if the reinforcement effect needs to be further improved，the distance between vibro-compaction points should be reduced to less than or equal to 3 m. For the loose coral sand layer with high-content fine particles，the optimized process of reverse insertion and vibration time increase can effectively improve the soil compactness between piles，but further reducing the distance between vibro-compaction points on this basis cannot significantly improve the final reinforcement effect.