The large-area vacuum preloading soft foundation treatment of Binzhou Port encountered a large area of reinforcement，a large thickness of silty sand interlayer，and a large buried depth during the construction process. In response to these problems，a process is adopted. That is：the outer boundary of the reinforcement area is sealed with a clay sealing wall；and the pressure film trenches between the partitions in the reinforcement area are artificially shallowly excavated，and the adjacent internal partition sealing films are alternately bonded at the pressure film trenches and then pressed with sandbags. The test results of the reinforcement effect show that the soil quality in the reinforcement area has been significantly improved. The technology can reduce the excavation workload，shorten the construction period，and save costs，which can provide a reference for similar projects.