The internal force of piled wharf transverse bent is usually simplified as a plane structure to calculate，but the end bent of the wharf as the stressed bent of the bow and stern cables，is affected by the adjacent structures. The pile foundation layout of end bent is different from other bents，and the simplified plane calculation cannot accurately reflect the force and deformation of the end bent. Based on the example of pile foundation layout design of Yushan ash loading wharf，we use the plane calculation method and space calculation method to compare and analyze different pile foundation layout schemes of the end bent of wharf structure under horizontal load，and obtain the differences of calculation results of internal force and deformation of each pile foundation under different calculation methods and pile foundation layout schemes. The results show that for the symmetric horizontal load，the axial force of pile foundation calculated by the plane calculation method is equivalent to that of pile foundation of end bent with the free end of wharf structure. For the asymmetric horizontal load，the axial force of pile foundation calculated by the plane calculation method is generally larger than that calculated by the space calculation method. The displacement of the wharf structure is reduced to a certain extent after the end bent is strengthened with double row piles.