In view of Luna 2×300 MW supercritical power plant project in Philippines,we study the structural design of pile-supported wharf under strong earthquake and huge wave.The structural schemes of integral and separated pile- supported wharf are compared,and the sensitivity of pile layout including bent spacing,pile diameter and pile inclination is studied.The conclusion is that the integral pile-supported wharf with larger bent spacing,larger diameter pile with larger inclination is more superior.