In order to realize the initial opening of 6 m water depth in the section from Wuhan to Anqing section of the Yangtze River main line,it is necessary to carry out waterway regulation on this section.The section of Huguang—Luohuzhou river is one of the sections.In order to provide the basis for determining the waterway regulation idea and forming the regulation plan,the physical model test was carried out in the section of Huguang—Luohuzhou river.The result of trend prediction experiment shows that although the channel conditions of this section can meet the scale requirements of 6 m channels at present,if no protective measures are taken,the current favorable channel conditions is likely to develop in an adverse direction,or even fail to meet the regulation target requirements.The results of the typical years and serial years tests of the scheme show that the implementation of the regulation project to a certain extent limits the erosion of the middle and high beaches in the riverside beach of Muerzhou,improves the inflow conditions of the Huguang waterway and the Luohuzhou waterway,and is further conducive to the maintenance of the main navigation channel conditions.