The slope stability of muddy deepwater channel in the open sea relates to the costs of its capital and maintenance dredging,and it is one of the most important problems in the design of waterway engineering.Taking 100 000 DWT waterway of Xuwei Port Area of Lianyungang Port as research object,we study the stability of its slope under the actions of medium wave and large wave on the basis of wave elements calculated by the wave model,which has been maturely applied in Lianyungang Sea.We also use the data of bathymetric survey near the slope for analysis.The results show that the slope angle of Xuwei 100 000 DWT waterway is properly determined from the perspective of wave dynamic,the wave dynamic in this sea will not cause adverse impact on the slope stability of the channel.