The dynamic analysis of high-pile wharf under the wave uplift force action is carried out by finite element software ANSYS. The results show that the internal force of dynamic and static calculation in all parts of the wharf structure is basically the same under the action of wave slowly varying pressure, so we can calculate the internal force through static analysis; but the internal force of dynamic calculation is much smaller than that of the static calculation under the action of wave impact pressure, therefore the dynamic analysis may be used to consider the interaction between wave impact pressure and high-pile wharf; High-pile wharf does not produce resonance phenomenon under the wave uplift force action because of the huge difference between wave uplift force frequency and structure natural frequency.