In the design of a large crude oil terminal, through optimizing the wharf axis and pier’s layout based on an in-depth study on the local natural conditions, we achieve the aim of saving shoreline resources,improving the berth conditions, and reducing the operating cost, optimize the fender design and improve the manufacturing technology of loading arm’s swivel joints through continuous exploration, carry out basic work for structures’ whole-life design by burying stress monitoring equipment in the main concrete structure, and apply the quick pulley for the first time in a formal project to enhance the constraints on the ship. Moreover, we work out an operation manual and summarize technical and management experience during implementation of the project. Many of the engineering design concepts and features provide a reference for similar dock construction.