After 30 years’reform and opening up, the coastal ports in Guangdong province has basically formed the development pattern of rational layout, structured, highly related to the regional distribution of productive forces. Now the port of Guangdong province is facing a new development environment, and the direction and ideas of the port development in the future need to be recombined. Based on the status and development environment of the coastal ports in Guangdong province and oriented to the implementation of the National Regional Development Strategy, the strategic thinking for the long-term development is studied in this paper to provide a reference for the relevant industry sectors to develop the strategic planning.