Digital waterway of Nanjing to Liuhe mouth consists of electronic channel chart system, comprehensive monitoring system, information management system and system support platform, etc. The comprehensive monitoring system, which is composed of remote sensing and control of waterway marks platform,ship monitoring platform, is the core of digital waterway system. After operation, this system plays an important role in the daily work of waterway maintenance and management such as dynamic monitoring of waterway marks information, dynamic monitoring of working ship, dynamic inspection of waterlevel and investigation and evidence collection of waterway marks being bumped and ship traffic accident. It improves work efficiency of waterway maintenance. With the progress of waterway science and technology, the comprehensive monitoring system will have more extensive application prospect.