To address the challenges in directly observing the internal deformation mechanisms and stability of high-piled wharves on soft foundations due to complex structures and significant 3D mechanical characteristics,the research is conducted on the evolution law of 3D deformation features and safety states of the high-piled wharf-slope system during construction period.A 3D numerical model consisting of multiple framed bents in independent structural sections of a typical project in Shanghai is built using the PLAXIS 3D platform.Pile-soil deformation responses under continuous construction conditions are simulated.Combined with the response surface methodology and Monte Carlo simulation,the failure probability and reliability index of the system are quantitatively evaluated.The results indicate that during slope excavation,④ mucky soft clay layer and ⑤ clay layer dominate the system deformation,contributing 66.7% of the crest settlement (＞40 cm),85.7% of the toe heave (＞20 cm),and 44.4% of the deep horizontal displacement.The application of equivalent loads at the pile head to simulate driving effects effectively controls toe heave.Furthermore,the combined diagonal-vertical pile structure significantly inhibits excavation-induced displacement and enhances horizontal resistance.Safety analysis demonstrates that the failure probability rises during excavation and decreases markedly during diagonal pile construction,with the reliability index remaining within safe limits throughout the cycle.The research results reveal the interaction mechanism between soft soil slopes and high-piled wharves and establish a reliability assessment framework integrating numerical models with data-driven methods,providing a theoretical basis and technological support for real-time safety early warning in complex structural engineering.